Solid-phase microwave assisted synthesis of curcumin analogs

…, R Alli, A SC Prabhakar, RR Alavala…

Index: Pore, Dinesh; Alli, Ramesh; Prabhakar, Achanta S. C.; Alavala, Rajashekar R.; Kulandaivelu, Umasankar; Boyapati, Shireesha Letters in Organic Chemistry, 2012 , vol. 9, # 6 p. 447 - 450

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Abstract

Turmeric contains three important analogs, curcumin, demethoxycurcumin (DMC) and bisdemethoxycurcumin (BDMC), collectively called as curcuminoids. Curcumin, the most abundant of these curcuminoids is reported to have antioxidant, anti-inflammatory, neuroprotective, antimicrobial, nematocidal, antimutagenic, anticarcinogenic, antiretroviral and chemopreventive activities. Curcumin (a symmetric β diketone) analogs 3a-e were ...