Tetrahedron Letters

Double Michael addition of dithiols to acetylenic carbonyl compounds under the influence of molecular sieve and dimethyl sulfoxide

T Kakinuma, T Oriyama

Index: Kakinuma, Tomoko; Oriyama, Takeshi Tetrahedron Letters, 2010 , vol. 51, # 2 p. 290 - 292

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Citation Number: 9

Abstract

Double Michael addition of dithiols such as 1, 3-propanedithiol and 1, 2-ethanedithiol to α, β- acetylenic carbonyl compounds in the presence of molecular sieve and dimethyl sulfoxide proceeds very smoothly to afford the corresponding β-keto 1, 3-dithianes and β-keto 1, 3- dithiolanes, respectively, in good to high yields.

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