Synthesis of some new pyrimidine and pyrimido [4, 5-d] pyrimidine derivatives

AA Fadda, EA El-Latif, S Bondock…

Index: Fadda, Ahmed A.; El-Latif, Ehab Abd; Bondock, Samir; Samir, Ahmed Synthetic Communications, 2008 , vol. 38, # 24 p. 4352 - 4368

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Citation Number: 11

Abstract

Abstract A convenient synthesis of a series of pyrimidine carbonitrile, thiopyrimidine, and pyrimidopyrimidine derivatives, via the reactions of the versatile, readily accessible 6-aryl-4- oxo-2-thioxo-hexahydro-pyrimidine-5-carbonitrile with the appropriate reagents, is described.