Samarium (II) Iodide-Mediated Synthesis of Chlorohydrins

B Castagner, P Lacombe, R Ruel

Index: Castagner, Bastien; Lacombe, Patrick; Ruel, Rejean Journal of Organic Chemistry, 1998 , vol. 63, # 13 p. 4551 - 4553

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Citation Number: 4

Abstract

The reductive coupling between a carbonyl and an organic halide with samarium diiodide produces the corresponding alcohol efficiently, as first shown by Kagan et al. in their introductory paper on SmI2. 1 It was also shown by several groups that these reactions did not proceed well when the carbonyl compounds were added subsequently to the halides and SmI2. 1, 2 A subset of these reactions, namely the samarium (II) iodide-mediated ...