A Convenient Halogenation Procedure for the Preparation of α??Halocarbonyl Compounds

SF Cheng, CS Lin, LK Liu

Index: Cheng, Sheng-Fan; Lin, Ching-Shan; Liu, Lilian Kao Journal of the Chinese Chemical Society (Taipei, Taiwan), 1997 , vol. 44, # 3 p. 309 - 312

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Citation Number: 8

Abstract

Abstract Except for substituted acetophenones (p-YC 6 H 4 COCH 3, Y= H, Br, CH 3 O), simple ketones, β-ketoesters and 1, 3-diketones reacted smoothly with a preformed homogeneous mixture of hydrochloric acid and potassium permanganate in acetonitrile to give moderate to good yields of the corresponding α-chlorocarbonyl compounds. Mixtures of α-chloro-and α, α-dichlorocarbonyl compounds were obtained for substituted ...