Organic & biomolecular chemistry

Copper (II)-mediated oxidative cyclization of enamides to oxazoles

AE Wendlandt, SS Stahl

Index: Wendlandt, Alison E.; Stahl, Shannon S. Organic and Biomolecular Chemistry, 2012 , vol. 10, # 19 p. 3866 - 3870

Full Text: HTML

Citation Number: 41

Abstract

Copper(II)-mediated C–H oxidation reactions have been the focus of extensive attention in recent years. 1,2 Many applications of these reactions are oxidative cyclizations involving heterofunctionalization of arene C–H bonds. 3 Two early examples, reported by the groups of Buchwald 3a and Nagasawa, 3b,c feature copper-catalyzed oxidative cyclization of substituted benzamidines and benzanilides to benzimidazoles (eqn (1)) and benzoxazoles (eqn (2)), respectively. In ...

Related Articles:

Copper-catalyzed oxidative cyclization of chalcone and benzylic amine leading to 2, 5-diaryl oxazoles via carbon–carbon double bond cleavage

[Liu, Dongfang; Yu, Jintao; Cheng, Jiang Tetrahedron, 2014 , vol. 70, # 6 p. 1149 - 1153]

Direct C–H Bond Arylation of (Benzo) oxazoles with Aryl Chlorides Catalyzed by N-Heterocyclic Carbene–Palladium (II)–1-Methylimidazole Complex

[Shen, Xiao-Bao; Zhang, Yun; Chen, Wen-Xin; Xiao, Zheng-Kang; Hu, Ting-Ting; Shao, Li-Xiong Organic Letters, 2014 , vol. 16, # 7 p. 1984 - 1987]

Synthesis of Oxazoles through Copper??Mediated Aerobic Oxidative Dehydrogenative Annulation and Oxygenation of Aldehydes and Amines

[Xu, Zejun; Zhang, Chun; Jiao, Ning Angewandte Chemie - International Edition, 2012 , vol. 51, # 45 p. 11367 - 11370 Angew. Chem.]

Iron??Promoted Practical One??Pot Synthesis of 2, 5??Disubstituted Oxazoles

[Chen, Songhui; Bai, Donghu; Shi, Feng; Li, Jian; Li, Chunju; Jia, Xueshun Chinese Journal of Chemistry, 2012 , vol. 30, # 7 p. 1464 - 1468]

Nickel??Catalyzed Direct C H Arylation and Alkenylation of Heteroarenes with Organosilicon Reagents

[Hachiya, Hitoshi; Hirano, Koji; Satoh, Tetsuya; Miura, Masahiro Angewandte Chemie - International Edition, 2010 , vol. 49, # 12 p. 2202 - 2205]

More Articles...