Synthesis and central nervous system depressant activity of new oxaza heterocyclic amides

G Pifferi, P Consonni, A Diena…

Index: Pifferi; Consonni; Diena; Rosselli del Turco Journal of medicinal chemistry, 1972 , vol. 15, # 8 p. 851 - 853

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Citation Number: 3

Abstract

suppress carrageenin-induced edema in rats and ultravioletinduced erythema in guinea pigs. Similarly, these compounds were without effect at 50 mg/kg per day against adjuvantinduced arthritis in rats. Aspirin is accepted as active in these assays at the indicated doses with a 99% frequency, and the thiazolylacetic acid 1 is active at these screening levels. Compound 2a was ineffective in the carrageenin edema and uv ...