Chemische Berichte

Enantioselective Catalysis, XIII. Preparative and Structural Chemistry of Chiral 3??(Diphenylphosphanyl)??pyrrolidiens and Their Palladium (II) Complexes

U Nagel, HG Nedden

Index: Nagel, Ulrich; Nedden, Hans Guenter Chemische Berichte, 1997 , vol. 130, # 3 p. 385 - 397

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Citation Number: 20

Abstract

Abstract The preparation of both enantiomers of 3-diphenylphosphanulpyrrolidiine (2) and several N-substituted derivatives together with two Pd Ii complexes of this ligand is reported. Form L-malic acid and L-hydroxyproline both enantiomers of 3-hydroxypyrrolidine are prepared without any problems due to epimerization. KPPh 2 in the presence of LiCl is shown to be the most effective reagent for the synthesis of 2. The reported X-ray structure ...