Tetraphosphine/palladium catalysed Suzuki cross-coupling reactions of aryl halides with alkylboronic acids

I Kondolff, H Doucet, M Santelli

Index: Kondolff, Isabelle; Doucet, Henri; Santelli, Maurice Tetrahedron, 2004 , vol. 60, # 17 p. 3813 - 3818

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Citation Number: 48

Abstract

Through the use of [PdCl (C3H5)] 2/cis, cis, cis-1, 2, 3, 4-tetrakis (diphenylphosphinomethyl) cyclopentane as a catalyst, a range of aryl bromides and chlorides undergoes Suzuki cross- coupling with alkylboronic acids in good yields. Several alkyl substituents such as ethyl, n- butyl, n-octyl, isobutyl or 2, 2-dimethylpropyl on the alkylboronic acids have been successfully used. The functional group tolerance on the aryl halide is remarkable; ...