Easy Access to 2-Alkyl and 2-Arylthiazolines Using a Modified Heteropolyacid Catalysis: Application to the Synthesis of Bacillamide A

F Fache, F Cros, O Piva, F Lefebvre

Index: Fache; Cros; Piva; Lefebvre Synthetic Communications, 2012 , vol. 42, # 14 p. 2098 - 2109

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Citation Number: 4

Abstract

A straightforward access to 2-alkyl and 2-arylthiazolines by condensation of β-aminothiols on nitriles, catalyzed by phosphotungstic acid (2%) under microwave irradiation, is described. This method has been directly applied to a short and efficient synthesis of bacillamide A (16). ... A straightforward access to 2-alkyl and 2-arylthiazolines by condensation of β-aminothiols on nitriles, catalyzed by phosphotungstic acid (2%) under microwave irradiation, is ...