The Journal of Organic Chemistry

Fluorocarbanion chemistry. A versatile synthesis of functionalized fluoro ketones

CG Krespan, BE Smart

Index: Krespan, Carl G.; Smart, Bruce E. Journal of Organic Chemistry, 1986 , vol. 51, # 3 p. 320 - 326

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Citation Number: 25

Abstract

Fluorocarbanions generated by the addition of an anion to a fluoro olefii can be trapped by fluoro esters, thereby providing a versatile, one-step synthesis of functionalized fluoro ketones. The most efficient anions include CN-, Nc, C6H50-, RO-, and RS-. The reaction has been extended in one case to prepare a sulfinate ester.