Transition??Metal??Free Atropo??Selective Synthesis of Biaryl Compounds Based on Arynes

…, A Berthelot, L Bonnafoux, A Panossian…

Index: Leroux, Frederic R.; Berthelot, Anais; Bonnafoux, Laurence; Panossian, Armen; Colobert, Francoise Chemistry - A European Journal, 2012 , vol. 18, # 45 p. 14232 - 14236

Full Text: HTML

Citation Number: 27

Abstract

The biaryl motif occupies an iconic role in chemistry, being a key structural feature of natural products, biologically active molecules, drugs, agrochemicals, and other novel optical and mechanical materials.[1] Furthermore, the stereogenic axes provide rigid molecular frameworks for highly efficient tools in asymmetric synthesis.[2] With the continuously increasing importance of axially chiral biaryl compounds as chiral auxiliaries and ligands ...