Heck reactions of aryl halides in phosphonium salt ionic liquids: library screening and applications

DA Gerritsma, A Robertson, J McNulty, A Capretta

Index: Gerritsma, David A.; Robertson, Al; McNulty, James; Capretta, Alfredo Tetrahedron Letters, 2004 , vol. 45, # 41 p. 7629 - 7631

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Citation Number: 70

Abstract

The Heck cross-coupling of aryl iodides and bromides with olefins proceeds in the phosphonium salt ionic liquid trihexyl (tetradecyl) phosphonium chloride (THP-Cl) in excellent yields. Furthermore, it is shown that the counter anion matched to the phosphonium cation exerts a measurable effect on the overall yield.