Nicotinamide??substituted complexes as redox markers. 1. Synthesis and UV investigation of rhenium and technetium mixed??ligand systems

…, H Spies, W Brandau, B Johannsen

Index: Kniess; Spies; Brandau; Johannsen Journal of Labelled Compounds and Radiopharmaceuticals, 1998 , vol. 41, # 7 p. 605 - 614

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Citation Number: 8

Abstract

Abstract In order to develop a redox delivery system for Tc radiotracers the synthesis of new nicotinamide and pyridinium salt-substituted Re (V) mixed-ligand complexes of the '3+ 1'type is described. The complexation of 99/99m Tc with these ligands was studied by thin layer chromatography and UV-VIS spectroscopy. The reduction of the pyridinium salt with sodium dithionite to the 1, 4-dihydropyridine was carried out on the free ligand and on the ...

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