Design and synthesis of spirocyclic compounds as HCV replication inhibitors by targeting viral NS4B protein

VWF Tai, D Garrido, DJ Price, A Maynard…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 24, # 10 p. 2288 - 2294

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Citation Number: 5

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... The current work extends these chemical series, 17, 18 and 19 resulting in compounds of novel structure that exhibit low-nM potency against HCV replicons. ...

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