Convenient Synthesis of 1, 2-Benzisothiazol-3 (2H)-ones by Cyclization Reaction of Acyl Azide

T Chiyoda, K Iida, K Takatori, M Kajiwara

Index: Chiyoda; Iida; Takatori; Kajiwara Synlett, 2000 , # 10 p. 1427 - 1428

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Citation Number: 15

Abstract

Abstract: 1, 2-Benzisothiazol-3 (2H)-one was synthesized by treatment of 2- mercaptobenzoic acid with diphenyl phosphoryl azide, followed by cyclization of the resulting acyl azide at low temperature, where Curtius rearrangement did not occur. 5-Amino- 1, 2-benzisothiazol-3 (2H)-one was similarly synthesized in one pot from 4- mercaptoisophthalic acid. Key words: acyl azide, cyclization, 1, 2-benzisothiazol-3 (2H)- ...