Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study
…, S Capaldi, E Carlsson, B Kobilka, CJ Loland…
Index: Chae, Pil Seok; Rana, Rohini R.; Gotfryd, Kamil; Rasmussen, Soren G.F.; Kruse, Andrew C.; Cho, Kyung Ho; Capaldi, Stefano; Carlsson, Emil; Kobilka, Brian; Loland, Claus J.; Gether, Ulrik; Banerjee, Surajit; Byrne, Bernadette; Lee, John K.; Gellman, Samuel H. Chemical Communications, 2013 , vol. 49, # 23 p. 2287 - 2289
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Citation Number: 24
Abstract
The development of a new class of surfactants for membrane protein manipulation,“GNG amphiphiles”, is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al.(Science, 2012, 337, 473).
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