Organic letters

Ruthenium-catalyzed tertiary amine formation from nitroarenes and alcohols

C Feng, Y Liu, S Peng, Q Shuai, G Deng, CJ Li

Index: Feng, Chao; Liu, Yong; Peng, Shengming; Shuai, Qi; Deng, Guojun; Li, Chao-Jun Organic Letters, 2010 , vol. 12, # 21 p. 4888 - 4891

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Citation Number: 51

Abstract

A highly selective ruthenium-catalyzed C− N bond formation was developed by using the hydrogen-borrowing strategy. Various tertiary amines were obtained efficiently from nitroarenes and primary alcohols. The reaction tolerates a wide range of functionalities. A tentative mechanism was proposed for this direct amination reaction of alcohols with nitroarenes.

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