Journal of fluorine chemistry

Nouvelle synthese de trifluoromethylcetones et d'/ga-bromo trifluoromethylcetones

JP Bégué, D Mesureur

Index: Begue, J. P.; Mesureur, D. Journal of Fluorine Chemistry, 1988 , vol. 39, p. 271 - 282

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Citation Number: 31

Abstract

Abstract We report a new method for the preparation of trifluoromethylketones, as an alternative to the use of organometallics. The condensation of phosphonium ylides with trimethylsilyl trifluoroacetate provides silyloxy enol ethers whose hydrolysis leads to trifluoromethylketones. Bromation of the same silyloxy enol ether is also a convenient preparation of/ga-bromo trifluoromethylketone.