Tetrahedron

Substitutions nucleophiles d'olefines fluorees—II

R Sauvêtre, J Normant, J Villieras

Index: Sauvetre,R. et al. Tetrahedron, 1975 , vol. 31, p. 897 - 903

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Citation Number: 14

Abstract

The nucleophilic substitution of compounds A CF CFCl (A RO, RS) proceeds by addition-elimination. The observed regioselectivity depends upon the nature of A. The stereospecificity is explained by steric hindrance in the transition state of the elimination step. Butyllithium also promotes a lithium—chlorine exchange.