A new synthesis of n-acyl aromatic α-amino acids—amidoalkylation of aromatic and heterocyclic compounds with glyoxylic acid derivatives
D Ben-Ishai, I Sataty, Z Bernstein
Index: Ben-Ishai,D. et al. Tetrahedron, 1976 , vol. 32, p. 1571 - 1573
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Citation Number: 64
Abstract
(Rtc-titudin fhr 1 'K I5 Jama? 1976. .4crrprtd~~~rpuh/icar~~~n .( Fthrua~ 19%) ... Abstract--The synthesis of N.acyl derivatives of aroma&c o-ammo acids S by rhc amdoalkylahons of aromatic and hetcrocychc compounds ulth glyonylic acid amide adducts is described. ... Aromatic amino acids of Ihc phcnylglycinc type (I) have found applications in the synthesis of semisynthetic pencillins and ccphalosporins.' Phcnylglycinc, p. hydroxphenylglycinc and 3,5-dichloro-% ...
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