New Synthesis of Diazepino [3, 2, 1??ij] quinoline and Pyrido [1, 2, 3??de] quinoxalines via Addition–Elimination Followed by Cycloacylation

PG Baraldi, E Ruggiero…

Index: Baraldi, Pier Giovanni; Ruggiero, Emanuela; Tabrizi, Mojgan Aghazadeh Journal of Heterocyclic Chemistry, 2014 , vol. 51, # 1 p. 101 - 105

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Abstract

Abstract This paper describes a convenient and efficient synthesis of new fused tricyclic diazepino [3, 2, 1-ij] quinolines and substituted pyrido [1, 2, 3-de] quinoxalines. o- Phenylenediamines are transformed in the tricycle nucleus in only a few-step synthetic sequence to produce ethyl 2, 8-dioxo-1, 2, 3, 4-tetrahydro-8H [1, 4] diazepino [3, 2, 1-ij] quinoline-7-carboxylate, ethyl 8-oxo-1, 2, 3, 4-tetrahydro-8H-[1, 4] diazepino [3, 2, 1-ij] ...

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