Reactions of carbene intermediates from the reaction of trialkyl phosphites with dialkyl benzoylphosphonates: intramolecular cyclisations of 2-substituted dialkyl …

…, PA Griffiths, K Karima, BJ Whitehead

Index: Griffiths, D. Vaughan; Griffiths, Penelope A.; Karim, Khalku; Whitehead, Belinda J. Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 6 p. 555 - 561

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Citation Number: 2

Abstract

The reaction of dialkyl benzoylphosphonates 1 with trialkyl phosphites leads to the formation of carbene intermediates 3 via the anionic intermediates 2. The carbene intermediates 3 (R= 2-PhO, 2-PhOCH2, and 2-PhS) have been generated by heating the corresponding 2- substituted dialkyl benzoylphosphonates with trimethyl phosphite and their subsequent reactions investigated. Reactions proceed either by intermolecular trapping of the carbene ...