The Journal of Organic Chemistry

Synthesis of (.+-.)-frullanolide: an application of radical closure

DLJ Clive, AC Joussef

Index: Clive, Derrick L. J.; Joussef, Antonio C. Journal of Organic Chemistry, 1990 , vol. 55, # 3 p. 1096 - 1098

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Citation Number: 26

Abstract

The sesquiterpene, frullanolide (l), is an allergy-producing substance that occurs in certain plants of the Frullania genus.'Several syntheses of this compound have been described $? we report here a new route in which radical cyclization is the essential step for constructing the a-methylene y-lactone unit.