Il Farmaco

Synthesis and biological evaluation of some new 3, 4-dihydropyrimidin-4-ones

J Modha, N Datta, H Parekh

Index: Modha, Jayesh; Datta, Neela; Parekh, Hansa Farmaco, 2001 , vol. 56, # 9 p. 641 - 646

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Citation Number: 19

Abstract

Condensation of 5-cyano-2-hydrazino-3-N-methyl-6-phenyl/p-chlorophenyl-3, 4- dihydropyrimidin-4-one (3a and 3b) with 2, 4-bisalkyl/arylamino-6-chloro-s-triazine (4) gave the corresponding 2, 4-bisalkyl/arylamino-6-[5′-cyano-3′-N-methyl]-6′-phenyl/p- chlorophenyl-3′, 4′-dihydropyrimidin-4′-one-2′-yl-hydrazino-s-triazines (5a–n and 6a– n). The compounds 4 have been prepared by the condensation of cyanuric chloride and ...

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