Synthesis and evaluation of a series of novel imidazolidinone analogues of 6-aminoflavone as anticancer and anti-inflammatory agents

S Moorkoth, KK Srinivasan, NG Kutty, A Joseph…

Index: Moorkoth, Sudheer; Srinivasan; Gopalan Kutty; Joseph, Alex; Naseer Medicinal Chemistry Research, 2013 , vol. 22, # 10 p. 5066 - 5075

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Citation Number: 4

Abstract

Abstract The flavone moiety is a potential pharmacophore known for its diverse range of pharmacological activities. Aminoflavones have recently been the subject of considerable attention as lead molecules in several cancer research projects. Imidazolidinone heterocycles represent another biologically active scaffold with known cytotoxic properties. In an attempt to provide synergistic cytotoxic activity, these two moieties have been ...