Tetrahedron Letters

β-Ketoimine as an efficient ligand for copper-catalyzed N-arylation of nitrogen-containing heterocycles with aryl halides

F Xue, C Cai, H Sun, Q Shen, J Rui

Index: Xue, Fei; Cai, Chengyi; Sun, Hongmei; Shen, Qi; Rui, Jiao Tetrahedron Letters, 2008 , vol. 49, # 28 p. 4386 - 4389

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Citation Number: 22

Abstract

An efficient copper catalyst system, Cu2O/β-ketoimine L1, for the N-arylation of nitrogen- containing heterocycles with aryl iodides and bromides has been developed. The system works well with the electron-rich,-neutral, and-deficient aryl bromides to afford the products in good to excellent yields.

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