Asymmetric synthesis of unusual α-amino acids

YN Belokon, KA Kochetkov, DY Borkin

Index: Belokon, Yuri N.; Kochetkov, Konstantin A.; Borkin, Dmitry A. Mendeleev Communications, 2003 , vol. 13, # 3 p. 132 - 134

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Citation Number: 5

Abstract

The synthesis of non-proteinogenic chiral α-amino acids is of considerable interest.1,2 Previously, we introduced 1, a chiral NiII complex of Schiff's base of glycine and (S)-o-[N-(N'- benzylprolyl)amino]benzophenone (BPB), as a useful substrate for the asymmetric synthesis of α-amino acids by different reac- tions of C–C bond formation.3,4 This approach has significant advantages including the simplicity of preparation of complex 1,5 a wide range of ...