A convenient and efficient route for the allylation of aromatic amines and α-aryl aldehydes with alkynes in the presence of a Pd (0)/PhCOOH combined catalyst system

…, H Wu, I Kadota, Y Yamamoto

Index: Patil, Nitin T.; Wu, Huanyou; Kadota, Isao; Yamamoto, Yoshinori Journal of Organic Chemistry, 2004 , vol. 69, # 25 p. 8745 - 8750

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Citation Number: 26

Abstract

The allylation of aromatic amines with alkynes proceeded smoothly in the presence of catalytic amounts of Pd (PPh3) 4 and benzoic acid. The allylation products were obtained in high yields in a regio-and stereoselective manner. The effect of various groups on the nitrogen atom of anilines was studied. Regardless of the substituent (electron withdrawing or electron donating) on the aromatic ring, the reaction proceeded well. Various ...

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