One-pot synthesis of phenylallyl substituted unsymmetrical ureas under microwave irradiation

LQ Chai, WP Chen, XQ Wang, JL Ge

Index: Chai, Lan-Qin; Chen, Wei-Peng; Wang, Xiao-Qiang; Ge, Jian-Lin Phosphorus, Sulfur and Silicon and the Related Elements, 2007 , vol. 182, # 11 p. 2491 - 2496

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Citation Number: 5

Abstract

A series of phenylallyl-substituted unsymmetrical ureas were synthesized in a one-pot procedure by reactions of cinnamoyl isocyanate, which was prepared from cinnamoyl azide by Curtius rearrangement, with various aromatic amines, 2-amino-5-aryl-1, 3, 4-thiadiazoles and 2-amino-5-aryloxymethylene-1, 3, 4-thiadiazoles under microwave irradiation. Compared to conventional methods, this synthesis has the advantages of mild reaction ...