Structures of cribochalines A and B, branched-chain methoxylaminoalkyl pyridines from the micronesian sponge, Cribochalina sp. Absolute configuration and …
GM Nicholas, TF Molinski
Index: Nicholas, Gillian M.; Molinski, Tadeusz F. Tetrahedron, 2000 , vol. 56, # 19 p. 2921 - 2927
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Citation Number: 30
Abstract
Two new 3-alkyl pyridines, cribochalines A (2) and B (3), were isolated from the North Pacific sponge Cribochalina sp. The known related oxime, ikimine A, was shown to be a 2.8: 1 mixture of the (S)-and (R)-enantiomers. Cribochaline A exhibited antifungal activity against Candida albicans ATCC and Fluconazole-resistant strains C. albicans 96–489, C. krusei and C. glabrata.
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