Iodination of anilines and phenols with 18-crown-6 supported ICl 2−

…, DP Kennedy, CD Incarvito, SC Burdette

Index: Mbatia, Hannah W.; Ulloa, Olbelina A.; Kennedy, Daniel P.; Incarvito, Christopher D.; Burdette, Shawn C. Organic and Biomolecular Chemistry, 2011 , vol. 9, # 8 p. 2987 - 2991

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Citation Number: 5

Abstract

A highly crystalline iodinating reagent,{[K· 18-C-6] ICl2} n, was synthesized in high yield (93%). The trihalide is supported by an 18-crown-6 macrocycle and forms a coordination polymer in the solid state. This reagent iodinates anilines and phenols efficiently under mild conditions. Controlled mono-iodination with anilines was easily achieved while poly- iodination was observed with phenols.