Synthesis of o-diorganylphosphino-substituted benzoic acids and their derivatives

YA Veits, EG Neganova, OS Vinogradova

Index: Veits; Neganova; Vinogradova Russian Journal of General Chemistry, 2005 , vol. 75, # 7 p. 1060 - 1068

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Citation Number: 6

Abstract

Abstract o-Substituted dialkyl-and alkylphenylphosphinobenzoic acids, as well as their esters, nitriles, and amides, including those containing three different substituents on the phosphorus atom, were prepared for the first time by two different synthetic procedures. The most general procedure involves metal-halogen exchange in bromo-and iodoarenes, followed by phosphorylation of the resulting lithium derivatives.