The discovery of tricyclic pyridone JAK2 inhibitors. Part 1: Hit to lead

T Siu, ES Kozina, J Jung, C Rosenstein…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 24 p. 7421 - 7425

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Citation Number: 17

Abstract

... JavaScript is disabled on your browser. Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... Using the same chemistry as shown in Scheme 1, several heteroatom variations as represented by 12, 13, and 14 (Fig. ...

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