Tetrahedron Letters

Free porphyrin catalyzed direct C–H arylation of benzene with aryl halides

YS Ng, CS Chan, KS Chan

Index: Ng, Yeuk Sze; Chan, Chung Sum; Chan, Kin Shing Tetrahedron Letters, 2012 , vol. 53, # 30 p. 3911 - 3914

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Citation Number: 35

Abstract

Biaryl motifs are widely present in a variety of natural products and drugs, 1 such as Diovan® and Micardis® as hypertension medicine (Fig. 1). Their sales are up to billion and possess large values. 2 and 3 A cheap and efficient way to prepare such fine chemicals with biaryl motif is of great interest. ... Structures of Diovan® and Micardis®. Structures of Diovan® and Micardis®. ... The aryl–aryl bond formation was first reported by Ullmann in 1901 using ...

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