Microbiological oxygenation of alicyclic amides

GS Fonken, ME Herr, HC Murray…

Index: Fonken,G.S. et al. Journal of Organic Chemistry, 1968 ,  vol. 33,  # 8  p. 3182 - 3187            

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Citation Number: 23

Abstract

Continuing our broad study of the microbiological oxygenation of simple monocyclic systems, a series of N-cycloalkylamides and N, N-dicycloalkylamides waa subjected to fermentation by Sporotrichum sulfurescm. Consonant with the hypothetical enzyme- substrate model proposed earlier, N-cyclododecylacetamide was monooxygenated at the 5, 6, and 7 positions, while a variety of N-cyclohexyhmides and N-cycloheptylamides ...