Synthesis, Characterization, and Mutagenicity of Nitrated 7 H-Dibenzo [c, g] carbazole and Its Phenolic Derivatives

W Xue, K LaDow, D Warshawsky

Index: Xue, Weiling; LaDow, Kathleen; Warshawsky, David Chemical Research in Toxicology, 1997 , vol. 10, # 4 p. 432 - 438

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Citation Number: 5

Abstract

The nitrated N-heterocyclic aromatic hydrocarbons (NAHs) are found in a variety of environmental sources; many of them have been determined to be mutagenic in short-term assays and/or carcinogenic in animal tests. In this laboratory, we synthesized and characterized nitrated 7 H-dibenzo [c, g] carbazole (DBC) and the nitrophenolic metabolites of DBC as potential mutagenic and carcinogenic xenobiotics. The nitro group was formed ...