Practical Synthesis of (±)??Venlafaxine

SP Chavan, DA Khobragade, M Thakkar…

Index: Chavan, Subhash P.; Khobragade, Dushant A.; Thakkar, Mahesh; Kalkote, Uttam R. Synthetic Communications, 2007 , vol. 37, # 22 p. 3901 - 3906

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Abstract

In connection with an ongoing program on the synthesis of antidepressants paroxetine 1 and venlafaxine 2 (Fig. 1), a technically and economically viable protocol1 View all references for the synthesis of antidepressant drug venlafaxine 2 was developed (Fig. 1, Scheme 1), which was followed by a similar synthesis by Rangappa et al.24. Basappa , Kavitha , CV and Rangappa , RS 2004. Bioorg. Med. Chem. Lett., 14: 3279–3281. ... Figure 1. Two of the most ...

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