A Convenient and Practical Synthesis of Anisoles and Deuterated Anisoles by Palladium??Catalyzed Coupling Reactions of Aryl Bromides and Chlorides

S Gowrisankar, H Neumann…

Index: Gowrisankar, Saravanan; Neumann, Helfried; Beller, Matthias Chemistry - A European Journal, 2012 , vol. 18, # 9 p. 2498 - 2502

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Citation Number: 19

Abstract

In recent years, palladium-and copper-catalyzed crosscoupling reactions have become useful tools for the synthesis of (hetero) aryl ethers.[1–3] Due to the presence of aromatic ether bonds in numerous natural products, pharmaceuticals, fragrances, cosmetics, and polymers,[4] further developments of efficient CÀO bond-forming reactions are of continuing interest for organic chemistry. In particular, methyl (hetero) aryl ethers (anisoles) represent ...

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