Optical resolution of racemic S??(Carboxymethyl) cysteine

A Kleemann, J Martens

Index: Kleemann, Axel; Martens, Juergen Liebigs Annalen der Chemie, 1982 , # 3 p. 1995 - 1998

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Abstract

Abstract Racemic S-(carboxymethyl) cysteine [(R, S)-2] obtained from racemic cysteine is resolved via its ammonium salt (R, S)-3 by preferential crystallization procedure. Furthermore,(R, S)-2 forms with optically active amines separable, diastereomeric salts. Thus,(1R, 2S)-2-amino-1-phenyl-1-propanol (4) affords optically pure (R)-S-(carboxymethyl) cysteine [(R)-2] in 93% yield. The resolution of (R, S)-2 is also possible with (R)-1- ...