Six-membered cyclic. beta.-keto esters by tandem conjugate addition-Dieckmann condensation reactions

RA Bunce, CR Harris

Index: Bunce, Richard A.; Harris, Christina R. Journal of Organic Chemistry, 1992 , vol. 57, # 25 p. 6981 - 6985

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Citation Number: 12

Abstract

OThe number of equivalenta used ia relative to diethyl (E)-2-heptenedioate. All reactione were run at-20 OC for 30-60 min. Stoichiometry was similar for other RMgX-CuCl except when R= vinyl, where 12 equiv of the reagent was necemary. More equiv-alenta of these reagenta did not significantly improve the yields.