Silver-mediated trifluoromethylation of aryldiazonium salts: conversion of amino group into trifluoromethyl group

…, J Feng, Y Ye, S Zhang, Y Zhang, J Wang

Index: Wang, Xi; Xu, Yan; Mo, Fanyang; Ji, Guojing; Qiu, Di; Feng, Jiajie; Ye, Yuxuan; Zhang, Songnan; Zhang, Yan; Wang, Jianbo Journal of the American Chemical Society, 2013 , vol. 135, # 28 p. 10330 - 10333

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Citation Number: 118

Abstract

A novel strategy for aromatic trifluoromethylation by converting aromatic amino group into CF3 group is reported herein. This method, which can be considered as trifluoromethylation variation of the classic Sandmeyer reaction, uses readily available aromatic amines as starting materials and is performed under mild conditions.