Journal of Heterocyclic Chemistry

Synthesis of pyridyl??and quinolyl??substituted 2??aminothiazoles

A Taurins, A Blaga

Index: Taurins,A.; Blaga,A. Journal of Heterocyclic Chemistry, 1970 , vol. 7, p. 1137 - 1141

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Citation Number: 31

Abstract

Abstract Five 2-amino-4-(x-pyridyl)-and 2-amino-4-(x-quinolyl) thiazoles have been synthesized by the condensation of thiourea with bromoacetylpyridines and-quinolines. The reaction of pyridyl pyridylmethyl ketones with thiourea and halogens produced four 2- aminothiazoles possessing pyridyl substituents in 4-and 5-positions on the thiazole ring. Treatment of N-(3-pyridyl)-and N-(3-quinoiyl) thiourea with α-bromoketones gave seven ...