Tetrahedron

Iodine-promoted silylation of alcohols with silyl chlorides. Synthetic and mechanistic studies

A Bartoszewicz, M Kalek, J Stawinski

Index: Bartoszewicz, Agnieszka; Kalek, Marcin; Stawinski, Jacek Tetrahedron, 2008 , vol. 64, # 37 p. 8843 - 8850

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Citation Number: 20

Abstract

An efficient silylating system for 1°, 2°, and 3° alcohols, consisting of a silyl chloride/N- methylimidazole/iodine, was developed. Synthetic and mechanistic aspects of this new reagent system, and particularly the role of iodine were investigated in detail using 1H NMR spectroscopy.

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