Canadian Journal of Chemistry

Nitrogen-and sulfur-containing models for metallo-enzymes. Part I. Synthesis and physical studies of 2 (2-pyridyl)-1, 3-dithioalkyl-2-propanols, 2 (2-pyridyl)-and 2 (2- …

NJ Curtis, RS Brown

Index: Curtis, N. J.; Brown, R. S. Canadian Journal of Chemistry, 1981 , vol. 59, p. 65 - 75

Full Text: HTML

Citation Number: 14

Abstract

Several compounds of the title class have been synthesized as small-molecule analogues for the metal-binding sites in such biochemical systems as ADH. The ligands containing pyridine and two thioethers do not bind divalent metals (Co2+, Zn2+, Cu2+, Ni2+), strongly suggesting that thioethers are poorly chelated. However, the analogues containing free SH groups bind divalent metals very strongly, producing complexes with limited solubility at ...

Related Articles:

New Syntheses of Substituted Pyridines via Bromine–Magnesium Exchange

[Trecourt, Francois; Breton, Gilles; Bonnet, Veronique; Mongin, Florence; Marsais, Francis; Queguiner, Guy Tetrahedron, 2000 , vol. 56, # 10 p. 1349 - 1360]

Aggregative activation in heterocyclic chemistry. Part 5.† Lithiation of pyridine and quinoline with the complex base BuLi· Me 2 N (CH 2) 2 OLi (BuLi· LiDMAE)

[Gros, Philippe; Fort, Yves; Caubere, Paul Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 24 p. 3597 - 3600]

Ru3 (CO) 12-Catalyzed Intermolecular Cyclocoupling of Ketones, Alkenes or Alkynes, and Carbon Monoxide.[2+ 2+ 1] Cycloaddition Strategy for the Synthesis of …

[Epsztajn, Jan; Bieniek, Adam Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 213 - 220]

N??[1??(Acyloxy) alkyl] heteroaryliumsalze in der Synthese, 3. Intramolekulare ortho??Acylierung einiger N??heteroaromatischer Ringsysteme

[Sobecki Chemische Berichte, 1908 , vol. 41, p. 4103]

More Articles...