Synthesis and stereochemistry of some 3-azabicyclo [3.3. 1] nonane derivatives

…, GR Yakhina, TV Khakimova, LV Spirikhin…

Index: Vafina; Yakhina; Khakimova; Spirikhin; Galin; Yunusov Russian Journal of Organic Chemistry, 2003 , vol. 39, # 1 p. 49 - 56

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Citation Number: 8

Abstract

Abstract Michael reactions of methyl (ethyl) 1-benzyl-4-oxopiperidine-3-carboxylates with a number of α, β-unsaturated carbonyl compounds result in formation of 6-and 6, 8-substituted methyl (ethyl) 3-benzyl-9-oxo-3-azabicyclo [3.3. 1] nonane-1-carboxylates. Stereochemical aspects of these reactions were studied, and some further transformations of the products were performed.

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