Tetrahedron letters

New synthetic “tricks” One-pot preparation of N-substituted phthalimides from azides and phthalic anhydride

J Garcia, J Vilarrasa, X Bordas, A Banaszek

Index: Garcia, Jordi; Vilarrasa, Jaume; Bordas, Xavier; Banaszek, Anna Tetrahedron Letters, 1986 , vol. 27, # 5 p. 639 - 640

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Citation Number: 41

Abstract

Abstract N-Substituted phthalimides can be obtained in very good yields, under essentially neutral conditions, by mixing or heating an alkyl (oraryl) azide, triphenylphosphine, and phthalic anhydride in benzene or toluene, in the presence of a catalytic amount of tetrabutylannionium cyanide. Application of the reaction into the domain of carbohydrates is promising.

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