Antioxidant properties of nitrocaffeic acids

JL Grenier, N Cotelle, P Cotelle, JP Catteau

Index: Grenier, Jean-Luc; Cotelle, Nicole; Cotelle, Philippe; Catteau, Jean-Pierre Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 4 p. 431 - 434

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Citation Number: 8

Abstract

A series of nitrodihydroxybenzenes and nitrocaffeic acids were prepared and their hydroxyl radical (OH°) and superoxide anion (O2−) scavenging activities and xanthine oxidase inhibition activities were evaluated. 2-Nitrocaffeic acid is the more potent O2− scavenger. 2- (and 5)-Nitrocaffeic acids are the more potent xanthine oxidase inhibitors.

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