Antioxidant constituents from rhubarb: structural requirements of stilbenes for the activity and structures of two new anthraquinone glucosides

H Matsuda, T Morikawa, I Toguchida, JY Park…

Index: Matsuda, Hisashi; Morikawa, Toshio; Toguchida, Iwao; Park, Ji-Young; Harima, Shoichi; Yoshikawa, Masayuki Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 1 p. 41 - 50

Full Text: HTML

Citation Number: 160

Abstract

The methanolic extracts from five kinds of rhubarb were found to show scavenging activity for DPPH radical and O2−. Two new anthraquinone glucosides were isolated from the rhizome of Rheum undulatum L. together with two anthraquinone glucosides, a naphthalene glucoside, and 10 stilbenes. In the screening test for radical scavenging activity of rhubarb constituents, stilbenes and a naphthalene glucoside showed activity, but anthraquinones ...

Related Articles:

Synthesis and biological evaluation of novel (E) stilbene-based antitumor agents

[Csuk, Rene; Albert, Sabrina; Siewert, Bianka; Schwarz, Stefan European Journal of Medicinal Chemistry, 2012 , vol. 54, p. 669 - 678]

Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure–activity relationship

[Murias, Marek; Handler, Norbert; Erker, Thomas; Pleban, Karin; Ecker, Gerhard; Saiko, Philipp; Szekeres, Thomas; Jaeger, Walter Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 21 p. 5571 - 5578]

Synthesis of radiolabeled stilbene derivatives as new potential PET probes for aryl hydrocarbon receptor in cancers

[Gao, Mingzhang; Wang, Min; Miller, Kathy D.; Sledge, George W.; Hutchins, Gary D.; Zheng, Qi-Huang Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 22 p. 5767 - 5772]

Simple synthesis of 5-substituted resorcinols: a revisited family of interesting bioactive molecules

[Alonso, Emma; Ramon, Diego J.; Yus, Miguel Journal of Organic Chemistry, 1997 , vol. 62, # 2 p. 417 - 421]

Synthesis of radiolabeled stilbene derivatives as new potential PET probes for aryl hydrocarbon receptor in cancers

[Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 22 p. 5767 - 5772]

More Articles...