Synthesis and pharmacological activity of 6H-and 6-alkyl-8-methylimidazo [1, 2-f] xanthines

…, SN Garmash, NA Klyuev, NI Romanenko

Index: Priimenko, B. A.; Samura, B. A.; Garmash, S. N.; Klyuev, N. A.; Romanenko, N. I. Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 2 p. 105 - 108 Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 2 p. 160 - 164

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Abstract

The IR spectra of 6H, 8-methyllmldazo [l, 2-f] xanthines (IV-XVlII) showed characteristic absorptions over the range 1720-1690 cm-* due to stretching vibrations of the amlde carbonyl groups (amide I bands). Absorption at 1680-1610 cm-I is attributed to stretching vibrations of the azomethlne group, although amlde II bands appear in this region together with stretching vibrations of the conjugated C-----Cbond [6].